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We conducted additional meta-regression analyses using random effects network meta-regression models to examine potential effect moderators such as the mean age of participants, the type of rating scales (clinician-rated versus self-rated), publication status (published versus dissertation), and therapy format (individual vs group).
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Radcliffe, Nathan; Review of Ophthalmology, "Changing Treatment Paradigms in Glaucoma.
Therefore, the more restrictive variation on the Rule of Five proposed in this analysis seems appropriate to predict drug candidates for passive transdermal delivery.
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Checklist items are designated "New Item" in the main text if they address a particular aspect of reporting that is novel to network meta-analyses; these are labeled S1 through S5.
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Although a distinction is frequently made between heterochromia that affects an eye completely or only partially (sectoral heterochromia), it is often classified as either (due to or ) or acquired, with mention as to whether the affected iris or portion of the iris is darker or lighter.
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By contrast, the other common tests exhibited either poor sensitivity (corneal staining, 54%; conjunctival staining, 60%; meibomian gland grading, 61%) or poor specificity (TBUT, 45%; Schirmer test, 51%).
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